Mesothelioma diagnosis just got significantly more effective thanks to a new testing method that combines preexisting tests already independently used to detect the cancer.  According to an article posted on Surviving Mesothelioma, researchers at Brigham and Women’s Hospital in Boston came to this conclusion after employing the experimental method on 48 patients suspected of having mesothelioma.  The result: a near doubling of the sensitivity rate of the tests.

The researchers, led by Rachel Factor, an instructor of pathology at Boston Medical Center, collected cells using cytological methods, which involves studying tissue taken from patients on a cellular level.  Cytological methods of detection are considered favorable because they depend upon small samples that do not require invasive techniques to acquire.  The flip side of this ease is that such methods can be inaccurate.  Looking at irritated but otherwise normal cells from the lung lining can look remarkably similar to mesothelioma, for example.

After harvesting the cells, the researchers subjected the samples to not one but two genetic tests.  The first, called karyotyping, involves analyzing the cells’ chromosomes to look for any irregularities that would point toward cancer.  The second, known as flourescent in situ hybridization, or FISH, uses fluorescent probes to detect specific lengths of DNA in chromosomes.  When the researchers applied the modified test to the 48 patients, they noticed a doubling in the detection of mesothelioma.

This is great news, obviously, but the test has room for improvement.  Chief among them is (still) accuracy.  Even after the aforementioned doubling in detection, the sensitivity of the test was still only marked at 60%.  That means that the opportunity for false-negative results is unacceptably high.  One way the researchers could improve the test’s sensitivity is by employing additional FISH probes.  The only problem with that is, many of these probes are not yet commercially available.  Additional research, experimentation, and studies are needed before this test can be fully perfected.  Still, this is a huge step in the right direction, one which may lead to an improvement in the early detection and treatment of this disease and the quality of life of its sufferers.

A Mesothelioma diagnosis is made by a doctor. Mesothelioma symptoms can vary depending on the person affected and how severe the illness is. Symptoms can include having a hard time breathing and/or swallowing, a loss of appetite and chest pain, for example. If you believe you have Mesothelioma or if you were exposed to asbestos, it may be ideal to visit a doctor.

How a Mesothelioma Diagnosis is Determined

There are several methods doctors will use to make a Mesothelioma diagnosis. A physical exam is usually the first step, and the doctor will want to ask questions regarding your medical and family history. MRIs and CT Scans may be used, as they can possibly show the fluid collection between the lung and chest wall that sometimes appears as a result of Mesothelioma, thus giving the indication that a person has it. A tissue biopsy can also be used for a Mesothelioma diagnosis.

These are merely examples — you will want to ask your doctor how your Mesothelioma diagnosis was made. You may also want to ask your doctor about how accurate the method of making your diagnosis was, and if it wasn’t thought to be highly accurate, if there’s another type of test you could undergo. If you aren’t happy with your doctor’s response, you may consider getting a second opinion.

Treatment After a Mesothelioma Diagnosis

If you have been diagnosed with Mesothelioma, you were likely referred to an oncologist or Mesothelioma specialist doctor for treatment. Though there is no proven cure for Mesothelioma, treatment is available. Around the country, doctors are experimenting with different kinds of treatments, one of them being pneumonectomy. This involves the surgical removal of a lung as well as intensive chemotherapy. This treatment might extend the life of a person who has Mesothelioma.

Long-term survival of Mesothelioma is very rare, and victims have a life expectancy of less than two years from the onset of symptoms. Sadly, it’s not unusual for a person to die just months after a Mesothelioma diagnosis.

If you would like more information about Mesothelioma diagnosis and treatments, call 1-888-370-0121 to speak to a resource person.